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NO CAS: 169869-90-3
Formula Molekul: C25H26FN3O7S
Berat Molekul: 531.55300
EINECS NO: NA
MDL NO: NA
Penerangan Produk:
Nama Produk: Exatecan Mesylate NO CAS: 169869-90-3
sinonim:
DX-8951;
Exatecan mesilate;
Exatecan (Mesylate);
Sifat Fizikal Kimia:
Rupa: Pepejal atau cecair
Ujian : Lebih daripada atau sama dengan 99.0 peratus
Exatecan mesylate is a semisynthetic, water{{0}}soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Exatecan Mesylate (DX8951f) is a topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 ug/mL) for cancer research.
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Cool tags: exatecan mesylate cas 169869-90-3, pengilang, pembekal, kilang, beli, dalam stok